Hypertension: For the treatment of hypertension; may be used alone or in combination with other antihypertensive agents.
Nephropathy in Type 2 Diabetic Patients: For the treatment of diabetic nephropathy with an increased serum creatinine and proteinuria (>300 mg/day) in patients with type 2 diabetes and hypertension.
Decreases the progression of nephropathy as measured by the occurrence of doubling serum creatinine or end stage renal disease (need for dialysis or renal transplantation).